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The YA50-4 extends the HM Instruments YA50 platform with a fourth SBS deck position, enabling more complex molecular biology protocols that require multiple reagent reservoirs or an additional plate. While the YA50-3 is well-suited for straightforward single-reagent transfer protocols, the YA50-4 supports multi-step workflows such as PCR setup with separate positive and negative control reservoirs, or NGS library preparation with sequential enzyme and buffer additions — all without manual reagent swapping between steps.
Like all YA50 models, the YA50-4 uses a fixed 96-channel air-displacement head with a 2–50 μL volume range, delivering accuracy of ≤1.5% at 20 μL and precision of ≤1% CV. The compact 580 × 350 × 580 mm footprint remains BSC-compatible, and the Android tablet control system provides intuitive protocol programming with pre-built templates.
Applications
PCR/qPCR setup with positive and negative control reservoirs
NGS library preparation with sequential enzyme additions (fragmentation + end-repair + ligation)
ELISA with conjugate and substrate in separate reservoirs
Column gradient dilution for concentration series
RNA in vitro transcription with NTP mix, buffer, and enzyme loaded simultaneously
Functional Performance
4 SBS deck positions eliminate reagent swapping for multi-step protocols
96-channel fixed head processes entire plate in one simultaneous pass
2–50 μL volume range with ≤1.5% accuracy and ≤1% CV at 20 μL
Separate tip racks per reagent type prevent cross-contamination
Compact 580 × 350 × 580 mm footprint fits inside Class II BSC
Android tablet control via Bluetooth or USB Type-C (PD)
Built-in gradient dilution function for concentration series
Universal tip compatibility with standard SBS-format tips
Adjustable dispensing speed for viscous and volatile liquids
Pre-built protocol templates for PCR, NGS, and ELISA workflows
Main Parameters
| Parameter | Specification |
|---|---|
| Model | YA50-4 |
| Pipetting principle | Air displacement |
| Channels | 96 (fixed) |
| Volume range | 2–50 μL |
| Accuracy at 20 μL | ≤1.5% |
| Precision (CV) at 20 μL | ≤1% |
| Deck positions | 4 |
| Plate format | Standard SBS |
Technical Parameters
| Parameter | Value |
|---|---|
| Pipetting principle | Air displacement |
| Number of channels | 96 (fixed) |
| Volume range | 2–50 μL |
| Accuracy | ≤1.5% at 20 μL |
| Precision (CV) | ≤1% at 20 μL |
| Deck positions | 4 |
| Plate format | Standard SBS |
| Control interface | Android tablet |
| Connectivity | Bluetooth, USB Type-C (PD) |
| Power supply | 180–264 VAC, 47–63 Hz, 220W |
| Dimensions | 580 × 350 × 580 mm |
| Weight | 26.6 kg |
| Compliance standard | GBT 41812-2022 |
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