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The HM-CWF1 Ultra-Micro Spectrophotometer is a compact, all-in-one biological analysis instrument designed for rapid quantification of nucleic acids and proteins in laboratory environments. Built on UV-Vis spectrophotometry and Beer-Lambert's Law (A = εcl), it provides accurate absorbance measurements at three fixed wavelengths — 230 nm, 260 nm, and 280 nm — along with a dedicated OD600 module for bacterial culture monitoring.
Unlike conventional cuvette-based photometers, the HM-CWF1 employs liquid column surface tension technology, allowing direct measurement of sample volumes as low as 0.5–2 µL without dilution, cuvettes, or capillary tubes. This consumable-free design minimizes sample loss and significantly reduces per-test costs, making it particularly suitable for labs handling precious or volume-limited biological samples.
The instrument integrates a UV-enhanced CMOS linear array sensor and a high-stability pulsed xenon lamp (PP value <0.5%), ensuring consistent photometric accuracy across extended use. A three-light-path switching mechanism (0.04 mm, 0.2 mm, 1.0 mm) extends the measurable concentration range to over 150 times that of standard UV-Vis spectrophotometers. The built-in Android 10 operating system with a 7-inch HD touchscreen, integrated thermal printer, and Wi-Fi/Ethernet connectivity delivers a fully self-contained workflow from sample loading to result archiving.
Applications / Testing Items
Nucleic acid quantification: dsDNA, ssDNA, RNA (total, mRNA)
Protein concentration measurement: BSA, IgG, and other common protein standards
Purity assessment: A260/A280 and A260/A230 ratios for nucleic acid quality control
OD600 bacterial culture monitoring for microbial growth studies
Cell lysate analysis in molecular biology workflows
Pre-sequencing library quantification in genomics research
Routine QC in biopharmaceutical manufacturing processes
Functional Performance / Features
Three fixed detection wavelengths (230/260/280 nm): Optimized for standard nucleic acid and protein absorbance measurements without full-wavelength scanning overhead.
OD600 bacterial culture module: Measures bacterial and other culture media concentration directly; OD600 absorbance range 0–4 Abs, stability ≤1%, repeatability ≤1%.
No-dilution, no-consumable design: Liquid column surface tension technology supports 0.5–2 µL direct measurement, eliminating cuvettes and capillary tubes.
Three-light-path automatic switching: Motor-controlled selection between 0.04 mm, 0.2 mm (high-concentration), and 1.0 mm (standard concentration) optical paths for a detection range equivalent to 0.04–300 A (10 mm path).
High-stability xenon lamp light source: Pulsed xenon lamp with PP value <0.5% ensures minimal baseline drift for reproducible results.
UV-enhanced CMOS linear array detector: Delivers absorbance precision of 0.003 Abs and accuracy of ±2% (0.76 Abs @ 260 nm).
Fast detection — results in under 6 seconds: Suitable for high-throughput screening and routine quality control in busy laboratory environments.
7-inch HD Android 10 touchscreen: Intuitive UI with dedicated modules for Nucleic Acid Test, Protein Test, OD600, and more, all accessible from the home screen.
Built-in thermal printer: Generates printed reports on-site without external peripherals.
Wi-Fi and Ethernet connectivity: Supports multi-mode data upload, batch export via USB, and remote software upgrades over the cloud.
7000 mAh lithium battery (21.6 V): Provides up to 8 hours of continuous operation, enabling flexible field and bench-top use.
Large data storage: Stores 10,000–100,000 entries, searchable and exportable via USB.
Main Parameters
| Parameter | Specification |
|---|---|
| Model | HM-CWF1 |
| Detection Module | Ultra-micro nucleic acid & protein detection, OD600 bacterial solution detection |
| Wavelength Range | 230 nm, 260 nm, 280 nm (three fixed wavelengths) |
| Sample Volume | 0.5–2 µL |
| Nucleic Acid Testing Range | 2–15,000 ng/µL (dsDNA) |
| Protein Detection Range | 0.05–400 mg/mL (BSA) |
| Detection Time | <6 s |
| OD600 Absorbance Range | 0–4 Abs |
Technical Parameters
| Parameter | Specification |
|---|---|
| Optical Path | 0.2 mm, 0.04 mm (high concentration); 1.0 mm (standard concentration) |
| Light Source | Xenon flashlight (pulsed xenon lamp) |
| Detector | UV-enhanced CMOS linear array sensor |
| Absorbance Precision | 0.003 Abs (0.2 mm optical path) |
| Absorbance Accuracy | ±2% (0.76 Abs @ 260 nm) |
| Absorbance Range | 0.04–300 A (equivalent to 10 mm optical path) |
| OD600 Absorbance Stability | ≤1% |
| OD600 Absorbance Repeatability | ≤1% |
| Fluorescence Detection | Not available |
| Operating System | Android 10 |
| Display | 7-inch HD color touchscreen |
| Connectivity | Wi-Fi, Ethernet, USB |
| Data Storage | 10,000–100,000 entries, searchable, exportable via USB |
| Power Adapter | 45 W fast charging |
| Battery Capacity | 21.6 V / 7000 mAh |
| Power Consumption | 25 W (standby: 10 W) |
| Size & Weight | 325 mm × 227 mm × 211 mm; 5.15 kg |
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