MR-785A Micro Raman Spectrometer

Product Introduction

The MR-785A is HM Instruments' versatile micro Raman spectrometer, engineered specifically for laboratories that routinely encounter fluorescence interference. By employing a 785 nm near-infrared excitation laser, this system dramatically suppresses the autofluorescence that plagues visible-wavelength Raman measurements on organic compounds, biological specimens, dyed textiles, and colored minerals — revealing clean Raman spectra where 532 nm systems often fail.

At the heart of the MR-785A is a 1200 gl/mm volume phase holographic grating blazed at 800 nm, paired with the Hamamatsu 11639 CMOS linear array detector featuring 2048 pixels and linearity exceeding 99.8%. This optical configuration delivers a wavenumber range of 200–3200 cm⁻¹ with 7 cm⁻¹ spectral resolution, capturing the most diagnostically important vibrational modes of pharmaceutical compounds, biological molecules, polymers, and organic chemicals. The rack-mounted microscope with 5x through 100x objectives and 25 μm spot size enables precise targeting of individual particles, cells, and micro-domains within heterogeneous samples.

The manual sample stage provides straightforward, vibration-free operation ideal for point analysis, quick identification tasks, and teaching environments. For laboratories that process a wide variety of fluorescence-prone samples — from pharmaceutical tablets and tissue sections to dyed fibers and geological inclusions — the MR-785A delivers consistent, interpretable spectra at an accessible price point. Learn more about choosing the right wavelength in our Raman spectrometer technical FAQ.

Applications

• Pharmaceutical tablet polymorph identification and active ingredient verification
• Biological tissue and cell analysis with minimal autofluorescence background
• Dyed textile fiber identification in forensic and quality control laboratories
• Organic chemical compound characterization for research and process development
• Colored mineral and gemstone analysis where visible excitation causes fluorescence
• Food contaminant and adulterant detection in safety screening applications
• Fluid inclusion analysis in geological samples with fluorescent host minerals
• Art and heritage science pigment analysis on fluorescence-prone historical artifacts

Functional Performance and Features

1. 785 nm near-infrared excitation suppresses autofluorescence from organic, biological, and colored samples, producing clean spectra unobtainable with visible-wavelength lasers
2. 1200 gl/mm volume phase holographic grating blazed at 800 nm maximizes diffraction efficiency at the excitation wavelength for optimal signal throughput
3. Hamamatsu 11639 CMOS detector with 2048 pixels and linearity exceeding 99.8% provides reliable quantitative analysis across the full spectral range
4. Wavenumber range of 200–3200 cm⁻¹ covers the fingerprint region and key functional group vibrations essential for organic and pharmaceutical compound identification
5. 7 cm⁻¹ spectral resolution distinguishes closely related polymorphs and isomers in pharmaceutical and chemical applications
6. Signal-to-noise ratio of 500:1 ensures clear spectral features even for weak Raman scatterers in biological and organic samples
7. System stability exceeding 99% over 8 hours of continuous operation supports batch analysis workflows and long acquisition sequences
8. Rack-mounted microscope with 5x, 20x, 50x, and 100x objectives and 25 μm spot size enables precise micro-area targeting
9. SpectrumFactory software with database matching, baseline correction (airPLS), and PCA clustering accelerates compound identification workflows
10. Integration time from 1 ms to 65 s accommodates both strongly and weakly scattering samples within a single measurement session

Main Parameters

Parameter	Value
Product Model	MR-785A
Excitation Wavelength	785 nm
Wavenumber Range	200–3200 cm⁻¹
Spectral Resolution	7 cm⁻¹
Grating	1200 gl/mm, 12.5 mm × 12.5 mm effective size, blazed at 800 nm
Detector	Hamamatsu CMOS linear array, 2048 pixels, linearity > 99.8%
Sample Stage	Manual platform
Microscope	Rack-mounted, 5x / 20x / 50x / 100x objectives
Spot Size	25 μm
Reference Price	$30,000

Technical Parameters

Parameter	Specification
Wavelength Resolution	2048 channels, 0.1 nm interval (minimum)
Signal-to-Noise Ratio	Normal mode 500:1
Acquisition Mode	Single / Continuous / External trigger
Dynamic Range	3000:1
Dark Noise	20 counts
A/D Converter	16-bit, 2 MHz (maximum)
Exposure Time	0.06 ms – 65 s
Integration Time	1 ms – 65 s
Optical Slit	25 μm (default)
Fiber Optic Interface	SMA905
Data Transfer Rate	100 fps (maximum)
Digital I/O	4 programmable digital GPIO; 1 analog output (integrated laser power controller)
External Trigger	5 ns low-latency, 5 ns–65 s programmable delay, retriggerable
Connectors	30-pin connector, including USB (480 Mbps) / TTL (3.3 V) / RS232 / RS485
System Stability	Laser >99.9%, Spectrometer >99.99%, Overall >99% (8-hour test after 15-min warm-up)

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